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The trio of Methylcobalamin, Pyridoxine and Folic Acid helps in bringing down the plasma level of homocysteine, the major risk factor for Atherosclerosis. Alpha Lipoic Acid prevents plaque formation in the arteries by preventing LDL oxidation. Thus this combination reduces the major risk factors for Atherosclerosis Antioxidant Benfotiamine exhibits direct antioxidative capacity and prevents induction of DNA damage in vitro. Inositol is a vitamin-like substance. Inositol is used for diabetic nerve pain, panic disorder, high cholesterol, insomnia,cancer, depression, schizophrenia, Alzheimer’s disease, attention deficit-hyperactivity disorder (ADHD), autism, promoting hair growth, a skin disorder called psoriasis, and treating side effects of medical treatment with lithium. It helps to reduce the excess biosynthesis and accumulation of a variety of glucose metabolites, including glyceraldeyde-3-phosphate and dihydroxyacetone phosphate. Increased concentrations of these glucose intermediates serve as a trigger to many of the mechanisms responsible for hyperglycemia-induced cell damage. Benfotiamine increases tissue levels of thiamine diphosphate, in turn increasing transketolase activity and resulting in a significant reduction in glucose metabolites. Inositol is synthesized from glucose-6-phosphate and metabolized to phosphatidylinositol, which makes up a small, but very significant, component of cell membranes. It helps to reduce the excess biosynthesis and accumulation of a variety of glucose metabolites, including glyceraldeyde-3-phosphate and dihydroxyacetone phosphate. Increased concentrations of these glucose intermediates serve as a trigger to many of the mechanisms responsible for hyperglycemia-induced cell damage. Benfotiamine increases tissue levels of thiamine diphosphate, in turn increasing transketolase activity and resulting in a significant reduction in glucose metabolites. Inositol is synthesized from glucose-6-phosphate and metabolized to phosphatidylinositol, which makes up a small, but very significant, component of cell membranes.

MK Medicine is a leading pcd franchise provider, contract manufacturer and hospital supplier of WHO-GMP certified Alpha Liopic Acid 100 mg Methylcobalamin 1500 mcg Vitamin B6 3 mg Folic Acid 1.5 mg Biotin Inositol Minarels Capsule

10x1x10 (Alu-Alu)

Alpha-lipoic acid is absorbed from the small intestine and distributed to the liver via the portal circulation and to various tissues in the body via the systemic circulation. Alpha-lipoic acid readily crosses the blood-brain barrier. It is found, after its distribution to the various body tissues, intracellularly, intramitochondrialy and extracellularly. Alpha-lipoic acid is metabolized to its reduced form, dihydrolipoic acid (DHLA), by mitochondrial lipoamide dehydrogenase.

Methylcobalamin:
Absorption of vitamin B12 from the GI tract may be decreased by aminoglycoside antibiotics, colchicine, extended-release potassium preparations, aminosalicylic acid and its salts, anticonvulsants (e.g., phenytoin, Phenobarbital, primidone), cobalt irradiation of the small bowel, and by excessive alcohol intake lasting longer than 2 weeks. Neomycin-induced malabsorption of vitamin B12 may be increased by concurrent administration of colchicine.

Alphalipoic Acid:
Alpha lipoic acid may improve blood sugar control, so people with diabetes who are taking medication to lower blood sugar, such as metformin, glyburide, should only take alpha lipoic acid under the supervision of a qualified health professional and have their blood sugar levels carefully monitored.

Inositol:
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with Inositol Nicotinate.

 

 

Important Notice:- The Database is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.