Artesunate 120 mg Injection
Treatment of uncomplicated falciparum malaria in areas where there is evidence of chloroquine, pyrimethamine/sulfadoxine, mefloquine and quinine resistance. It should always be administered together with mefloquine in full therapeutic dose.
Treatment of severe falciparum malaria in areas where there is evidence of quinine resistance. Radical cure is then effected with a full course of an effective oral antimalarial.
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1 Vial
Drug-induced fever can occur.
Neurotoxicity has been observed in animal studies but not in humans. In view of the uncertainty about toxic effects, caution should be exercised when more than one 3-day treatment is given.
Cardiotoxicity has been observed following administration of high doses.
Generally well-tolerated
Cardiotoxicity (high doses)
Neurotoxicity observed in animal studies
Drug induced fever
Skin rash
Peak Plasma Time: within 1 hr
Half-Life, Elimination: 40-50 min
Protein Bound: ~70%
Metabolites: dihydroartemisinin, active
Excretion: urine, feces
Mechanism of Action
Unclear, may inhibit DNA replication & transcription
The powder for injection is difficult to dissolve and care should be taken to ensure that it is completely dissolved before parenteral administration. It should always be used immediately following reconstitution. If the solution is cloudy or a precipitate is present, the parenteral preparation should be discarded.
Important Notice:- The Database is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.
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