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Deflazacort belongs to a group of medicines called corticosteroids. It is sometimes referred to simply as an oral steroid.

Corticosteroids like deflazacort are used to treat a wide variety of conditions. Some examples include autoimmune diseases (for example, systemic lupus erythematosus (SLE), autoimmune hepatitis, sarcoidosis), joint and muscle diseases (for example, rheumatoid arthritis), and allergies and asthma. They are also used in the treatment of some cancers.

Deflazacort works by interfering with the release of certain chemicals in your body which cause inflammation.

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Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking deflazacort it is important that your doctor knows:

  • If you have high blood pressure.
  • If you have had a heart attack, or if you have any other heart problems.
  • If you have any problems with the way your liver works, or if you have any problems with the way your kidneys work.
  • If you (or a close family member) have either sugar diabetes or an eye condition called glaucoma.
  • If you have any of the following conditions: an underactive thyroid, ‚thinning‚ of the bones (osteoporosis), epilepsy, a condition causing muscle weakness (called myasthenia gravis), a stomach ulcer, or a bowel disorder.
  • If you have ever had a mental health problem.
  • If you are pregnant or breast-feeding. (Oral steroids like deflazacort can be taken while you are expecting or breast-feeding; however, it is important that your doctor knows about the baby.)
  • If you have any kind of infection at the moment, or if you have ever had tuberculosis (TB).
  • If you have ever had an unwanted blood clot in an artery or a vein.
  • If you have recently had, or are about to have, any vaccinations.
  • If you are taking or using any other medicines. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines.
  • If you have ever had an allergic reaction to a medicine, or if you have ever developed muscle pain after taking a steroid medicine.

Along with its useful effects, deflazacort can cause unwanted side-effects which your doctor will discuss with you. The benefits of taking an oral steroid usually outweigh the side-effects; however, they can sometimes be troublesome. The table below contains some of the most common ones associated with deflazacort. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer‚s printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer‚s information leaflet in the reference section below.

Although not everyone experiences side-effects, and some will improve as your body adjusts to the new medicine, speak with your doctor or pharmacist if you become concerned about any of the following:

Common deflazacort side-effects What can I do if I experience this?
Tummy (abdominal) pain, indigestion, feeling sick Stick to simple foods. If you are sick (vomit) and there is blood present, you must speak with your doctor straightaway
Muscle weakness or feeling tired Do not drive and do not use tools or machines while affected
Mood or behavioural changes, especially at the beginning of treatment If you become confused, irritable or start having worrying thoughts about harming yourself, speak with your doctor straightaway
Difficulties sleeping, headache, increased weight, and irregular periods in women If any of these become troublesome, speak with your doctor
Increased risk of getting an infection If you become ill, make an appointment to see your doctor straightaway
Long-term treatment with deflazacort may cause other unwanted effects If you have any symptoms which are causing you concern, you should arrange to see your doctor for advice
If any one take other drugs or over the counter products at the same time, the effects of Deflazacort Tablet may change. This may increase your risk for side effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Deflazacort Tablet may interact with the following drugs and products:
  • ACE inhibitors
  • Acetazolamide
  • Adrenergic neuron blockers
  • Antacids
  • Antidiabetics
  • Aspirin
  • Before starting the treatment, read the manufacturer‚s printed information leaflet from inside the pack and any additional information you are given by your doctor. These will give you more information about deflazacort and will also provide you with a full list of side-effects which you could experience from taking it.
  • Your doctor or pharmacist will tell you how many tablets to take for each dose. For an adult, the dose range is usually from ½-3 tablets daily, although it may be higher than this if you are acutely unwell. Take your dose in the morning during breakfast. Swallow the tablet with a drink of water. Children are sometimes prescribed a dose to take on alternate days only.
  • If you forget to take a dose at your usual time, take it as soon as you remember (with something to eat). If you do not remember until the following day, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
  • Continue to take deflazacort until your doctor tells you to stop. Stopping taking the tablets suddenly can cause problems so your doctor will want you to reduce your dose gradually over a period of time if/when this becomes necessary.

Important Notice:- The Database is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.