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Prochlorperazine is a medication used to treat symptoms of schizophrenia, severe nausea and vomiting, and anxiety. It belongs to a class of drugs called phenothiazines and works by blocking certain receptors in the brain that are involved in the regulation of mood and behavior. It is available in various forms such as tablets, suppositories, and injection.Common side effects include drowsiness, dry mouth, and dizziness. It can also cause tardive dyskinesia, a condition that causes involuntary movements of the face and tongue, in long-term use. Consult with your doctor before taking it, especially if you have a history of blood disorders, heart disease, or prostate problems.

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Prochlorperazine must carry a black-box warning about an increased risk of death when used in elderly patients with psychosis related to dementia. The medicine is not approved for treating patients with dementia-related psychosis. Using prochlorperazine increases the risk of a serious movement disorder called tardive dyskinesia. The condition may remit once the drug is stopped. If you are taking prochlorperazine regularly, you should not stop taking it without first talking to your doctor. If you have the eye condition glaucoma, be sure to tell your doctor. Prochlorperazine may affect intraocular pressure, which can be dangerous.

Common Side Effects of Prochlorperazine

Side effects reported by those on prochlorperazine include:

  • Drowsiness
  • Difficulty falling or staying asleep
  • Dizziness
  • Increased appetite, weight gain
  • Dry mouth
  • Blurred vision
  • Decreased sexual ability in men

If these symptoms seem severe or persist, tell your doctor.

Severe Side Effects of Prochlorperazine

If you have any of these side effects, contact your doctor right away, as they can be serious:

  • Fever
  • Confusion
  • Fast, irregular heartbeat
  • Stiffness in muscles
  • Sweating
  • Breathing or swallowing problems
  • Rash, hives, itching, swelling of eyes, face or other parts
  • Yellow skin, eyes
  • Erection lasting for hours

Prochlorperazine is a Pregnancy Category C drug, according to the FDA. That means harm to a woman‚s fetus cannot be ruled out. If you are pregnant, you should talk to your doctor about the benefits of taking prochlorperazine versus the potential risks to the baby. The drug may interfere with the results of home pregnancy tests. If you suspect you are pregnant while taking prochlorperazine, see your doctor. Prochlorperazine is excreted in the breast milk of nursing mothers. Ask your doctor if it would be better to stop the drug or stop breastfeeding.

Important Notice:- The Database is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.