Metoprolol Succinate eq to Metoprolol Tartrate 50mg (ER) Amlodipine 5mg Tablet
Medicine Overview OF Metoprolol
Metoprolol is a beta-adrenergic blocker used in hypertension, angina, acute myocardial infarction, supraventricular tachycardia, ventricular tachycardia, congestive heart failure, and prevention of migraine headaches.
When to use
Hypertension, angina pectoris, adjunct in hyperthyroidism, migraine prophylaxis, stable symptomatic heart failure, cardiac arrhythmias, prevention or control of arrhythmias on induction of anesthesia, adjunct in the early management of acute myocardial infarction (AMI)
How It Works
Metoprolol blocks ß1 adrenergic receptors of cardiomyocytes, reduces Na+ (sodium) uptake and slows down K+ (potassium) release. It also suppresses the norepinephrine-induced increase in the Ca+ (calcium) leak and the spontaneous Ca+ release, which are the major triggers for atrial fibrillation.
Medicine Overview OF Telmisartan
Telmisartan an angiotensin II receptor blocker indicated in the treatment of hypertension
When to use
Hypertension
How It Works
Telmisartan is a angiotensin II receptor antagonist. It exerts antihypertensive activity by preventing angiotensin II from binding to angiotensin II receptor type 1, thus inhibiting the vasoconstricting and aldosterone-secreting effects of angiotensin II.
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Metoprolol
Bradycardia, hypotension, arterial insufficiency, chest pain, congestive heart failure (CHF), oedema, palpitation, syncope, gangrene,dizziness, fatigue, depression, confusion, headache, insomnia, short-term memory loss, nightmares, somnolence, pruritus, rash, increased psoriasis, reversible alopecia, sexual dysfunction/impotence, Peyronie‚s disease, diarrhoea, constipation, flatulence, gastrointestinal (GI) pain, heartburn, nausea, xerostomia, agranulocytosis, musculoskeletal pain, blurred vision, dry eyes, oculomucocutaneous syndrome, tinnitus, dyspnoea, bronchospasm, wheezing, rhinitis, cold extremities, heart failure, heart block, bronchospasm
Telmisartan
Upper respiratory tract infection, dizziness, back pain, sinusitis, pharyngitis, diarrhoea, slight elevations in liver enzymes, rarely angioedema, rash, pruritus, urticaria
Report to the physician immediately if the patients are having any of these following symptoms:
- Nasal congestion
- Headache
- Dizziness
- Back pain
- Leg pain
- Muscle cramps
- Fatigue
- Neutropenia
- Chest pain
- Cough
- Bronchitis
- Diarrhoea
- Gastritis
- Anaemia
- Hypoglycaemia
- Hyperkalaemia
- Hypotension
Metoprolol
Caution should be taken in patients with :
- Myasthenia gravis
- Heart failure
- Bronchospastic disease
It may mask the symptoms of hyperthyroidism and hypoglycaemia.Report to the physician if the patients are allergic to the active ingredients and any other drugs.
Telmisartan
Caution should be taken in patients on prolonged :
- Diuretic therapy
- Patients with renal artery stenosis
- Aortic or mitral stenosis
- Obstructive biliary disease
- Renal and mild to moderate hepatic impairment
Report to the physician if the patients are allergic to the active ingredients and any other drugs.
Important Notice:- The Database is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.
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