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Ofloxacin is a quinolone antibiotic used for treating certain kinds of bacterial infections (ear infectons, urinary tract infections) and also useful in pelvic inflammatory disease (PID). It belongs to the fluoroquinolone class of antibiotics and it help to stops the multiplication of bacteria by inhibiting the reproduction and repair of their genetic material (DNA).
Cefixime Trihydrate is a cephalosporin antibiotic ued to treat infections caused by bacteria and used to treat pneumonia, Bronchitis, Gonorrhea and Ear, Lungs, Throat and urinary tract infections.
It has been demonstrated by recent studies concomitant administration of an Cefixime trihydrate and Ofloxacin dry syrup shows significantly better symptoms relief compared with the modest improvement of Typhoid fever, Urinary tract infection, Respiratory tract infection and Bone and joint infection.

● Typhoid fever
● Urinary tract infection
● Respiratory tract infection
● Nosocomial infections
● Soft tissue infections
● Skin infection
● Bone and joint infection

MK Medicine is a leading pcd franchise provider, contract manufacturer and hospital supplier of WHO-GMP certified Cefixime 50 mg Ofloxacin 50 mg Dry Syrup

30 ml
  • Dry mouth.
  • Diarrhoea.

Cefixime Trihydrate:

It is bactericidal beta-lactam antibiotic (such as penicillins). Cefixime disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity. The final transpeptidation step in the synthesis of the peptidoglycan is facilitated by transpeptidases known as penicillin-binding proteins (PBPs). PBPs bind to the D-Ala-D-Ala at the end of muropeptides (peptidoglycan precursors) to crosslink the peptidoglycan.

Ofloxacin:

Ofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, which is an enzyme necessary to separate replicated DNA, thereby inhibiting cell division. The fluoroquinolones interfere with DNA replication by inhibiting an enzyme complex called DNA gyrase.

BEFORE TAKING THIS MEDICINE TELL THE DOCTOR ABOUT ANY MEDICAL PROBLEMS AN ALLERGIES THAT CHILD HAS NOW OR HAS HAD.
This dry syrup is a combination of cefixime trihydrate and ofloxacin and both has unique mode of action because cefixime help disrupt the synthesis of the peptidoglycan layer of bacterial cell walls and ofloxacin inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, which is an enzyme necessary to separate replicated DNA, thereby inhibiting cell division.

Important Notice:- The Database is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.